The use of Curcumin in reducing patient’s discomforts after rhinoplasty.

Abstract

Background: Congestion and inflammation are important causes of discomfort following rhinoplasty. In the preset study, for the first time, we aimed to evaluate the effects of Curcumin on reduction of these symptoms.

Methods: This is a randomized clinical trial that was performed in 2022-2023 in Isfahan on all healthy individuals that were candidates of rhinoplasty due to cosmetic issues. 110 patients were randomized into two groups. The first group of patients received Curcumin with the lowest dosage: 250 mg capsules on a daily basis. The second group of patients were assigned to placebo group. Data collection tools in this study were Sino-nasal Outcome Test (SNOT-22) scale and nasal obstruction septoplasty effectiveness (NOSE) scale. These scales were completed for patients before surgery, 1 week, 2 weeks and 1 month after surgeries.

Results: All patients had significant reduction in both SNOT-22 and NOSE scores that showed improvements in their symptoms (P< 0.001). Within 1 week after the surgeries, patients in the Curcumin group had significantly lower SNOT-22 and NOSE scores compared to the placebo group (P< 0.001)

Conclusion: The use of Curcumin capsules after rhinoplasty is associated with significant increase in improvement of patient’s discomforts including nasal congestion, sneezing, coughing, discharge from throat, facial pain, fatigue and nasal obstruction. We recommend that this drug should be used in similar situations.